About Cerebral Protection

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Cerebral Protection

For brain metabolism, energy is derived from circulatory provision of oxygen and glucose. Surgery, anaesthesia, peri-operative stresses or other etiological factors can lead to decrease in oxygen supply leading to ischemia, with consequent interruption of metabolic process. This Ischemia stimulates active responses in the brain, which may persist long after substrate delivery has been restored....

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Cerebral protection during CPB

Despite advances in surgical, anesthetic, and neuroprotective strategies, cerebral injury after cardiac surgery remains a significant source of post-operative morbidity and is responsible for an increasing proportion of peri-operative deaths. Technological advancements have allowed cardiac surgery to be performed on a progressively older and sicker population who, in turn, are at increased risk...

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Cerebral Protection During MitraClipImplantation

OBJECTIVES This study sought to assess the feasibility and safety of using a filter-based cerebral protection system (CPS) during MitraClip implantation and to report on the histopathologic analysis of the captured debris. BACKGROUND Stroke is one of the serious adverse events associated with MitraClip therapy. METHODS Between July 2014 and March 2015, 14 surgical high-risk patients (age 75 ! 7...

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P 98: Neuroinflammation and Nanomedicine,How about Cerebral Palsy

Cerebral palsy (CP) is the most common motor disability in children, usually occurring during fetal development; before, during, or shortly after birth, or during infancy. CP takes place in about 2.1 per 1,000 live births .There is no exact reason but birth injury or inflammation of the central nervous system, infections and hypoxia are related risk factors of this disease. Often, symptoms incl...

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Cerebral Protection During Cardiac Surgery

Despite many advances in perioperative care, cerebral injury from cardiac surgery remains an important source of patient morbidity and mortality. This injury has a range of clinical manifestations, including stroke and encephalopathy, which occur in 1–3% and 10–15% of patients, respectively. Postoperative cognitive dysfunction (POCD) is more common, affecting 15–40% of patients 1 month after su...

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ژورنال

عنوان ژورنال: The Annals of Thoracic Surgery

سال: 2018

ISSN: 0003-4975

DOI: 10.1016/j.athoracsur.2017.07.004